San Pancrazio is a deconsecrated church in Florence, Italy. It is located in the square with the same name, behind Palazzo Rucellai. It is today home to the museum dedicated to the sculptor Marino Marini.
The church was built in the early Christian age, and is documented from 931; according to the historian Giovanni Villani, it would have been founded by Charlemagne. The annexed monastery was created in 1157, while the church was restored end enlarged from the 14th century. Giovanni Rucellai commissioned Leon Battista Alberti to build a chapel on the church's side (the only part still consecrated today), which was finished in 1467. This includes the notable tempietto del Santo Sepolcro (Small temple of the Holy Sepulchre, inspired by the church of the same name in Jerusalem), also by Alberti, covered by polychrome marbles and tarsias. The cloister houses a fresco by Neri di Bicci.
The church was modified in the 18th and 19th centuries, and, from 1808, it served the seat of the city's lottery, then as a tribunal and then as a tobacco factory.